Description:
Vanguard Plus 5/CV is a freeze-dried preparation of attenuated strains
of CD virus CAV-2 CPI virus and CPV plus a liquid preparation of
inactivated CCV with an adjuvant. The CPV fraction is high titer
(>107.0 TCID50/dose) and was attenuated by low passage (35 passes
from the canine isolate with a maximum of 2 additional passes allowed
for production) on the canine cell line which gives it the immunogenic
properties capable of overriding maternal antibody interference. Some
puppies in the field may have higher levels of maternal antibodies than
those evaluated in our pivotal efficacy study. All viruses were
propagated on established cell lines. The liquid component is used to
rehydrate the freeze-dried component which is packaged with inert gas
in place of vacuum.
Contains penicillin and streptomycin as preservatives.
